Concerning the limitations of person safety and difficulties in nodes repair, placement, search and rescue caused by complex or unreachable special areas where the Wireless Sensor Network (WSN) deployed in, an autonomous mobile strategy of carrier in WSN was proposed. Firstly, the localization of the carrier with fewer anchor nodes was realized by combining the maximum likelihood method and Received Signal Strength Indication (RSSI). Then, relying on the mathematical model, carrier moved autonomously in WSN by acquiring current position information and target node coordinates to amend the direction angle and select the next target node. The simulation results show that the proposed strategy can ensure the carrier to reach the destination along the shorter path and in less time, and the higher the density of sensor nodes is, the more likely this strategy will succeed. The WSN with 130, 180 and 300 nodes were simulated respectively, and the success rate was as high as 96.7%.